Real-Time Feedback Fuzzy Control of Mean Arterial Pressure in Postsurgerical Patients at Cardiac Intensive Care Unit

Seminars

Title	Real-Time Feedback Fuzzy Control of Mean Arterial Pressure in Postsurgerical Patients at Cardiac Intensive Care Unit
Speaker	Hao Ying, Ph.D. Professor, Department of Electrical and Computer Engineering Wayne State University, Detroit, Michigan 48202, USA
Time	October 16, 2006 (Monday), 12:00 p.m.
Place	L105
Organized by	Faculty of Science and Technology, University of Macau

Abstract

In this seminar, we present a fuzzy control system to provide closed-loop control of mean arterial pressure (MAP) in postsurgical patients in a cardiac surgical intensive care unit setting, by regulating intravenous infusion of sodium nitroprusside (a vessel dilation drug). The fuzzy controller was mathematically proved to be a nonlinear proportionalintegral controller whose proportional gain and integral gain inherently adjusted continuously according to error and rate change of error of the process output (e.g., blood pressure). The gains became larger when the pressure was far from the desired pressure setpoint and smaller when it was close to the setpoint, resulting in more dynamic and stable control performance than the regular PI controller, especially when a linear process with time-delay or a nonlinear process was involved. Clinical trial results showed that the average percentage of time in which MAP stayed between 90% and 110% of the MAP setpoint was 89.31%, with a standard deviation of 4.96%, which were much better than manual control of the nurses. These were calculated based on 12 patient trials, with total trial time of 95 hours and 13 minutes. Accomplished in the late 1990’s, this is the world’s first real-time fuzzy control application in clinical medicine.

Biography

Professor Hao Ying has published one research monograph/advanced textbook entitled Fuzzy Control and Modeling: Analytical Foundations and Applications (IEEE Press, 2000), 74 peer-reviewed journal papers, and 102 conference papers. He is an Associate Editor for 4 international journals and is also a Member of Editorial Board for the journal Advances in Fuzzy Sets and Systems. He was a Guest Editor for four journals. He is an elected board member of the North American Fuzzy Information Processing Society (NAFIPS). He served as Program Chair for The 1994 and 2005 NAFIPS Conferences, as the Publication Chair for the 2000 IEEE International Conference on Fuzzy Systems, and as a Program Committee Member for over 20 international conferences. He was invited to serve as reviewer for 50 international journals.